Description
Vitronectin (VTN), a member of the pexin family, is an abundant glycoprotein found in serum, the extracellular matrix and bone. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. VTN consists of three domains: the N-terminal Somatomedin B domain, a central domain with hemopexin homology, and a C-terminal domain also with hemopexin homology.
VTN promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpins (serine protease inhibitors). It has been speculated to be involved in hemostasis, cell migration and tumor malignancy.
Only logged in customers who have purchased this product may leave a review.
Reviews
There are no reviews yet.