IFN-γ ELISA Kit, Mouse
$529.00
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse IFN-γ. The Mouse IFN-γ ELISA is for research use only. Not for diagnostic or therapeutic procedures.
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Description
Interferon gamma (IFN-γ) is a dimerized soluble cytokine that is the only member of the type II class of γ interferons. IFN-γ, or type II interferon, is a cytokine that is critical forinnate and adaptive immunity against viral, some bacterial and protozoal infections. IFN-γ is an important activator of macrophages and inducer of Class II major histocompatibility complex (MHC) molecule expression. Aberrant IFN-γ expression is associated with a number of autoinflammatory and autoimmunediseases. The importance of IFN-γ in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFN-γ is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 Th1 and CD8 cytotoxic T lymphocyte (CTL) effector T cells onceantigen- specific immunity develops.
The role of IFN-γ as a disease marker has been demonstrated for a number of different pathological situations including infections, autoimmune diseases, transplant rejection, allergy and diabetes.
Additional information
| Weight | 1 lbs |
|---|---|
| Dimensions | 8 × 6 × 4 in |
| Sensitivity | |
| Standard Curve | 15.63 – 1000 pg/ml |
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