CXCL10 / IP-10 ELISA Kit, Mouse
$529.00
This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of mouse IP-10. The Mouse CXCL10/IP-10 ELISA is for research use only. Not for diagnostic or therapeutic procedures.
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Description
C-X-C motif chemokine 10 (CXCL10), also known as Interferon gamma-induced protein 10 (IP-10), is an 8.7 kDa protein that belongs to the CXC chemokine family. IP-10 is secreted by several cell types in response to IFN-γ. These cell types include monocytes, endothelial cells and fibroblasts. IP-10 has been attributed to several roles, such as chemoattraction for monocytes/macrophages, T cells, NK cells, and dendritic cells, promotion of T cell adhesion to endothelial cells, antitumor activity, and inhibition of bone marrow colony formation and angiogenesis.
IP-10 shares a common receptor, CXCR3, with the chemokine MIG, but has been shown to play a distinct role in host defense in infections. IP-10 is involved in allergic contact dermatitis reactions and other allergic diseases. It appears during immune-mediated processes, in inflammation of the nervous system and in Alzheimer’s disease. Its involvement in the regulation of fibroproliferation following inflammatory lung injury has been described.
Additional information
| Weight | 1 lbs |
|---|---|
| Dimensions | 8 × 6 × 4 in |
| Sensitivity | |
| Standard Curve | 312.50 – 20000 pg/ml |
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