11β-HSD1 rabbit pAb
$148.00 – $248.00
hydroxysteroid 11-beta dehydrogenase 1(HSD11B1) Homo sapiens The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011].
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Description
Application:
Western Blot analysis of K562 cells using 11β-HSD1 Polyclonal Antibody. Antibody was diluted at 1:500.
Western Blot: 1/500 – 1/2000.
IHC-p: 1:100-1:300.
ELISA: 1/10000.
Not yet tested in other applications.
Formula:
PBS with 0.02% sodium azide and 50% glycerol pH 7.4.
Storage:
Store at -20°C. Avoid repeated freeze-thaw cycles.
Additional information
| Weight | 1 lbs |
|---|---|
| Dimensions | 8 × 6 × 4 in |
| Size | 100ug, 50ug |
| Reactivity | Human; Mouse; Rat |
| Source | Rabbit |
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