Polyclonal Antibody (pAb)
Polyclonal Antibody (pAb)
A polyclonal antibody is derived from multiple clones of B cells that produce antibodies against different epitopes of the same antigen. Unlike monoclonal antibodies, polyclonal antibodies are a mixture of various antibody types, which are produced when an animal (usually a rabbit, goat, or sheep) is immunized with an antigen. The animal's immune system then generates a variety of antibodies that recognize different parts of the antigen.
We offer polyclonal antibodies that detect targets of Human, Mouse, Rat, etc. species., we also offer secondary antibodies that detect IgG of human, mouse, rat , etc.
Products
11β-HSD1 rabbit pAb
hydroxysteroid 11-beta dehydrogenase 1(HSD11B1) Homo sapiens The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Mutations in this gene and H6PD (hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)) are the cause of cortisone reductase deficiency. Alternate splicing results in multiple transcript variants encoding the same protein.[provided by RefSeq, May 2011].
