Monoclonal Antibody (mAb)
Monoclonal Antibody (mAb)
A monoclonal antibody is a type of antibody that is made by identical immune cells, all of which are clones of a unique parent cell. These antibodies are specific to a single epitope (a particular part of an antigen). They are produced by fusing an antibody-producing B cell with a myeloma cell to form a hybridoma, which can then be cultured to produce large quantities of the antibody.
We offer Monoclonal antibodies that detect targets of Human, Mouse, Rat, etc. species. We also offer recombinant monoclonal antibodies.
Products
a-actinin (4A12) Mouse mAb
α-Actinin belongs to the spectrin family of cytoskeletal proteins. α-Actinin is necessary for the attachment of actin filaments to the Z-lines in skeletal muscle cells, and to the dense bodies in smooth muscle cells. The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and therefore coordinated contractions between sarcomeres in the horizontal axis.
